姓名：霍聪德           职称：教授、博士生导师

学科专业：有机化学          Email：huocongde@nwnu.edu.cn

 【个人简介】

2005年在兰州大学获理学博士学位；2005-2007香港理工大学博士后；2007-2009加拿大麦吉尔大学博士后。

    【研究领域和兴趣】

单电子转移反应是最微小的一种化学变化，却会对有机化合物的结构与反应性产生深远的影响，与经历双电子过程的极性反应形成良好的互补。我们长期的研究兴趣在于发展经历单电子转移过程的新反应并研究其反应机理。利用单电子转移过程进行氨基酸以及肽的位点选择性修饰是我们当前研究的重点。此外，对于绿色化学和药物化学也具有普遍的兴趣。

    【主持科研项目】

国家自然科学基金 (22271234)，2022

国家自然科学基金 (21961033)，2019

国家自然科学基金 (21562037)，2015

甘肃省自然科技基金 (1506RJZA122)，2015

霍英东教育基金会高等院校青年教师基金基础性研究课题 (141116)，2014

陇原青年创新人才扶持计划，2014

国家自然科学基金 (21262029)，2012

教育部博士点基金新教师类课题，2011

教育部留学回国人员科研启动基金，2011

国家自然科学基金 (21002080)，2010

教育部科学技术研究重点项目 (210232)，2010

甘肃省青年科技基金(1107RJYA026)，2010

甘肃省留学人员科技活动项目择优资助，2010

437必赢会员中心自然科学类青年教师科研基金项目 (NWNU-LKQN-09-11)，2009

    【获奖】        

437必赢会员中心优秀研究生导师，2021

甘肃省自然科学奖三等奖（排名：1）, 2021

蒂姆化学期刊奖 (Thieme Chemistry Journal Award)，2019

       甘肃省青年科技奖，2018

       甘肃省普通高校青年教师成才奖，2017

       甘肃省高等学校科学研究优秀成果奖一等奖 (排名：1)，2017

       437必赢会员中心“青年教师教学大赛”三等奖，2017

       甘肃省“飞天学者特聘计划”青年学者，2016

       甘肃省自然科学奖二等奖 (排名：3)，2016

       甘肃省优秀硕士学位论文指导教师，2016

       甘肃省高等学校科学研究优秀成果奖一等奖 (排名：3)，2016

       437必赢会员中心青年教师教学科研之星，2016

       美国化学会三年会员奖 (3-Year Membership Award to the American Chemical Society)，2015

       甘肃省高校科技进步奖三等奖 (排名：2)，2012

    【教学】      

高等有机化学（化工院高年级本科生、硕士研究生、博士研究生）

有机化学（化学、化工、生命科学、生物技术、制药等专业本科生）

学科导引（理科拔尖基地班本科生）、专业导引（化学专业本科生）

       有机制备实验（化工院、生科院本科生）

    【代表性研究论文】

        01, Congde Huo*, Yong Yuan, Mingxia Wu, Xiaodong Jia, Xicun Wang, Fengjuan Chen, Jing Tang, Auto-Oxidative Coupling of Glycine Derivatives, Angewandte Chemie International Edition 2014, 53, 13544-13547.

02, Jiayuan Wang, Youwan Ye, Tongzhi Sang, Chenxing Zhou, Xiazhen Bao, Yong Yuan, and Congde Huo*, C(sp³)–H/C(sp³)–H Dehydrogenative Radical Coupling of Glycine Derivatives, Organic Letters 2022, 24, 7577–7582.

03, Guozhe Guo, Yong Yuan, Xiazhen Bao, Xuehui Cao, Tongzhi Sang, Jiayuan Wang, Congde Huo*, Photocatalytic redox-neutral approach to diarylmethanes, Organic Letters 2021, 23, 6936−6940.

04,Jun Li,Yong Yuan,*Xiazhen Bao,*Tongzhi Sang,Jie Yang, Congde Huo*, Visible-light induced intermolecular oxyimination of alkenes, Organic Letters 2021, 23, 3712-3717.

05,Wei Jiang, Yajun Wang, Pengfei Niu, Zhengjun Quan, Yingpeng Su, Congde Huo*,Double-Oxidative Dehydrogenative (DOD) [4+2]-Cyclization/Oxidative Aromatization Tandem Reaction of Glycine Derivatives with Ethylbenzenes, Organic Letters 2018, 20, 4649-4653.

    06, Haitao Li, Songhai Huang, Yajun Wang, Congde Huo*, Oxidative Dehydrogenative [2+3]-Cyclization of Glycine Esters with Aziridines Leading to Imidazolidines, Organic Letters 2018, 20, 92-95.

07, Congde Huo*, Jing Tang, Haisheng Xie, Yajun Wang, Jie Dong, CBr₄ Mediated Oxidative C–N Bond Formation: Applied in the Synthesis of Imidazo[1,2-α]pyridines and Imidazo[1,2-α]pyrimidines, Organic Letters 2016, 18, 1016-1019.

    08, Congde Huo*, Fengjuan Chen, Yong Yuan, Haisheng Xie, Yajun Wang, Iron Catalyzed Dual-Oxidative Dehydrogenative (DOD) Tandem Annulation of Glycine Derivatives with Tetrahydrofurans, Organic Letters 2015, 17, 5028-5031.

09, Congde Huo*, Yong Yuan, Fengjuan Chen, Jing Tang, Yajun Wang, Copper-Catalyzed Aerobic Oxidative Dehydrogenative Formal [2+3] Cyclization of Glycine Esters with α-Angelicalactone: Approach to Construct Poly-substituted Pyrrolidones, Organic Letters 2015, 17, 4208-4211.

10,Jia Liang,Ying Fu,* Xiazhen Bao,* Lanlan Ou, Tongzhi Sang, Yong Yuan, Congde Huo*, Cyanation of glycine derivatives, Chemical Communications, 2021, 57, 3014–3017.

11, Jiayuan Wang, Yingpeng Su,* Zhengjun Quan,* Jun Li, Jie Yang, Yong Yuan, Congde Huo*, Visible-light promoted a-alkylation of glycine derivatives with alkyl boronic acids, Chemical Communications, 2021, 57, 1959–1962.

12, Jie Wang, Xiazhen Bao, Jiayuan Wang, Congde Huo*, Peroxidation of 3,4-Dihydro-1,4-benzoxazin-2-ones, Chemical Communications 2020, 56, 3895-3898.

       13, Congde Huo*, Jie Dong, Yingpeng Su, Jing Tang, Fengjuan Chen, Iron-Catalyzed Oxidative Sp³ Carbon-Hydrogen Bond Functionalization of 3,4-Dihydro-1,4-benzoxazin-2-ones, Chemical Communications 2016, 52, 13341-13344.

       14, Congde Huo*, Yajun Wang, Yong Yuan, Fengjuan Chen, Jing Tang, Auto-Oxidative Hydroxysulfenylation of Alkenes, Chemical Communications 2016, 52, 7233-7236.

15, Congde Huo*, Mingxia Wu, Fengjuan Chen, Xiaodong Jia, Yong Yuan, Haisheng Xie, Catalytic amounts of CBr₄ mediated dehydrogenative coupling of isochromans with aromatic ketones, Chemical Communications 2015, 51, 4708-4711.

16,Pengfei Niu, Jingya Yang,* Yong Yuan,* Yongxin Zhang, Chenxing Zhou, Xiazhen Bao, Congde Huo*, Photocatalyzed redox-neutral decarboxylative alkylation of heteroaryl methanamines, Green Chemistry, 2021, 23, 774–779.

17, Congde Huo*, Chougu Sun, Cheng Wang, Xiaodong Jia, Wenju Chang, Triphenylphosphine-m-sulfonate/Carbon Tetrabromide as an Efficient and Easily Recoverable Catalyst System for Friedel-Crafts Alkylation of Indoles with Carbonyl Compounds or Acetals, ACS Sustainable Chemistry & Engineering 2013, 1, 549-553.

18, Guozhe Guo, Yong Yuan,* Shuocheng Wan, Xuehui Cao, Yali Sun, Congde Huo*, K₂S₂O₈ promoted dehydrative cross-coupling between α,α-diaryl allylic alcohols and thiophenols/thiols, Organic Chemistry Frontiers2021, 8, 2990–2996.

19, Jie Wang, Jun Li, Yuanyuan Wei, Jingya Yang, Congde Huo*,Copper-catalyzed oxidative phosphonation of 3,4-Dihydro-1,4-benzoxazin-2-ones, Organic Chemistry Frontiers2018, 5, 3534-3537.

20, Yongxin Zhang, Wei Jiang, Xiazhen Bao*, Yifeng Qiu*, Yong Yuan, Caixia Yang, Congde Huo*, Photocatalyzed reverse polarity oxidative Povarov reaction of glycine derivatives with maleimides, Chinese Journal of Chemistry2021, 39, 3238-3244.

【代表性综述论文】

01, Congde Huo, Tak Hang Chan*, A novel liquid-phase strategy for organic synthesis using organic ions as soluble supports, Chemical Society Reviews 2010, 39, 2977-3006.

02, Xiazhen Bao,Wei Jiang,Jia Liang, Congde Huo*, One-Electron Oxidative Dehydrogenative Annulation and Cyclization Reactions, Organic Chemistry Frontiers2020, 7, 2107-2144.

03, Pengfei Niu, Jun Li, Yongxin Zhang, Congde Huo*, One-electron Reduction of Redox-active Esters to Generate Carbon-centered Radicals, European Journal of Organic Chemistry2020, 2020, 5801-5814.

04, Xiazhen Bao, Jun Li, Wei Jiang, Congde Huo*, Radical-Mediated Difunctionalization of Styrenes, Synthesis 2019, 51, 4507-4530.