张博生 副教授

437必赢会员中心，437必赢会员中心，甘肃，兰州，730070

学科专业：有机化学

Email：zhangbsh@foxmail.com, zhangbsh@nwnu.edu.cn

【简历】

博士，副教授，2020年6月毕业于兰州大学功能有机分子化学国家重点实验室，获理学博士学位（导师：梁永民 教授）；同年入职437必赢会员中心。从事过渡金属催化和有机方法学研究，在Catellani反应和自由基反应研究中取得了一系列成果，发表学术论文二十篇余篇。其中，第一作者（共同第一作者）在J. Am. Chem. Soc., ACS Catal., Chem. Commun., Org. Chem. Front., Org. Lett. 等重要学术期刊发表SCI论文十余篇，其中有两篇被被国际著名评述杂志《Synfact》选为亮点并作重要评论。博士论文《钯催化C-H活化串联反应及烯炔的氟烷基化研究》入选2019-2020学年甘肃省优秀博士论文。Web of Science数据库论文被引400余次，h指数（h-index）为12。

【研究项目】

1.国家自然科学基金（青年科学基金项目）(22101232)，主持

2.甘肃省青年科技基金项目(21JR7RA151)，主持

3.甘肃省高等学校创新基金项目(2021A-004)，主持

4.437必赢会员中心青年教师科研能力提升计划（骨干）项目（No. NWNU-LKQN2020-04），主持。

【研究兴趣】

1. 过渡金属催化的C-H活化串联反应（Pd/NBE化学）

2. 过渡金属迁移反应，如1,4-钯迁移

【代表论文】

1. Zhang, B.-S.; Li, Y.; Zhang, Z.; An, Y.; Wen, Y.-H.; Gou, X.-Y.; Quan, S.-Q.; Wang, X.-G.; Liang, Y.-M.*, Synthesis of C4-Aminated Indoles via a Catellani and Retro-Diels–Alder Strategy. J. Am. Chem. Soc. 2019, 141 (24), 9731-9738. (SCI 一区, IF 15.419) (Hightlighted by CBG and huaxuejia)

2. Zhang, B.-S.; Li, Y.; An, Y.; Zhang, Z.; Liu, C.; Wang, X.-G.; Liang, Y.-M., Carboxylate Ligand-Exchanged Amination/C(sp3)–H Arylation Reaction via Pd/Norbornene Cooperative Catalysis. ACS Catal. 2018, 8 (12), 11827-11833. (SCI 一区, IF 13.084) (Hightlighted by Synfacts and X-Mol)

3. Zhang, B.-S.*; Wang, F.; Gou, X.-Y.; Yang, Y.-H.; Jia, W.-Y.; Liang, Y.-M.*; Wang, X.-C.; Li, Y.*; Quan, Z.-J.*, Palladium-Catalyzed Synthesis of Tricyclic Indoles via a N–S Bond Cleavage Strategy. Org. Lett. 2021, 23 (19), 7518-7523. (SCI 一区, IF 6.005)

4. Zhang, B.-S.*; Yang, Y.-H.; Wang, F.; Gou, X.-Y.; Wang, X.-C.*; Liang, Y.-M.*; Li, Y.*; Quan, Z.-J.,* Reductive Coupling of Aryl Halides via C‐H Activation of Indene. Chin. J. Chem. 2021, 39 (6), 1573-1579. (SCI 二区, IF 6.000, 中国期刊)

5. Zhang, B.-S.; Li, Y.; Gou, X.-Y.; Zhang, Z.; An, Y.; Wang, X.-G.; Liang, Y.-M.*, DMAP and PivOH-promoted amination/allenization reaction. Chem. Commun. 2020, 56 (64), 9202-9205. (SCI 一区, IF 6.222)

6. Zhang, B.-S.*; Wang, F.; Yang, Y.-H.; Gou, X.-Y.; Qiu, Y.-F.; Wang, X.-C.; Liang, Y.-M.*; Li, Y.*; Quan, Z.-J.,* Synthesis of C4-Substituted Indoles via a Catellani and C–N Bond Activation Strategy., Org. Lett. 2020, 22 (21), 8267-8271. (SCI 一区, IF 6.005)

7. Zhang, B.-S.; Gao, L.-Y.; Zhang, Z.; Wen, Y.-H.; Liang, Y.-M., Three-component difluoroalkylation and trifluoromethylthiolation/trifluoromethylselenolation of π-bonds. Chem. Commun. 2018, 54 (10), 1185-1188. (SCI 一区, IF 6.222) (Hightlighted by Synfacts)

8. Zhang, B.-S.; Hua, H.-L.; Gao, L.-Y.; Liu, C.; Qiu, Y.-F.; Zhou, P.-X.; Zhou, Z.-Z.; Zhao, J.-H.; Liang, Y.-M., Palladium-catalyzed arene C–H activation/ketone C–H functionalization reaction: route to spirodihydroindenones. Org. Chem. Front. 2017, 4 (7), 1376-1379. (SCI 一区, IF 5.155, 中国TOP期刊)

9. An, Y.#; Zhang, B.-S.#（共同第一作者）; Ding, Y.-N.; Zhang, Z.; Gou, X.-Y.; Li, X.-S.; Wang, X.; Li, Y.; Liang, Y.-M.*, Palladium-catalyzed C–H glycosylation and retro Diels–Alder tandem reaction via structurally modified norbornadienes (smNBDs). Chem. Sci. 2021, 12, 13144-13150. (SCI 一区, IF 9.825). (Hightlighted by CBG)

10. Gou, X.-Y.#; Zhang, B.-S.# （共同第一作者）; Wang, X.-G.; Shi, W.-Y.; Liu, H.-C.; An, Y.; Zhang, Z.; Liang, Y.-M.* Visible-light-induced ligand-free RuCl3 catalyzed C–H phosphorylation in water. Chem. Commun. 2020, 56, 4704-4707. (SCI 一区, IF 6.222)

11. An, Y.; Zhang, B.-S.; Zhang, Z.; Liu, C.; Gou, X.-Y.; Ding, Y.-N.; Liang, Y.-M.* A carboxylate-assisted amination/unactivated C(sp2)–H arylation reaction via a palladium/norbornene cooperative catalysis. Chem. Commun. 2020, 56 (44), 5933-5936. (SCI 一区, IF 6.222)

12. Zhang, Z.; Zhang, B.-S.; Li, K.-L.; An, Y.; Liu, C.; Gou, X.-Y.; Liang, Y.-M.*, Palladium-Catalyzed Amination/Dearomatization Reaction of Indoles and Benzofurans. J. Org. Chem. 2020, 85 (12), 7817-7839. (SCI 二区, IF 4.354)

13. Hua, H.-L.; Zhang, B.-S.; He, Y.-T.; Qiu, Y.-F.; Hu, J.-Y.; Yang, Y.-C.; Liang, Y.-M.*, Copper-catalyzed difluoromethylation of propargylamide-substituted indoles: synthesis of mono- and bis-difluoromethylated indoloazepinone derivatives. Chem. Commun. 2016, 52 (68), 10396-10399. (SCI 一区, IF 6.222)

14. Hua, H.-L.; Zhang, B.-S.; He, Y.-T.; Qiu, Y.-F.; Wu, X.-X.; Xu, P.-F.; Liang, Y.-M., Silver-Catalyzed Oxidative Cyclization of Propargylamide-Substituted Indoles: Synthesis of Phosphorated Indoloazepinones Derivatives. Org. Lett. 2016, 18 (2), 216-219. (SCI 一区, IF 6.091)

15. Wang, X.-G.; Li, Y.; Liu, H.-C.; Zhang, B.-S.; Gou, X.-Y.; Wang, Q.; Ma, J.-w.; Liang, Y.-M., Three-Component Ruthenium-Catalyzed Direct meta-Selective C-H Activation of Arenes: A New Approach to The Alkylarylation of Alkenes. J. Am. Chem. Soc. 2019, 141, 13914-13922. (SCI 一区, IF 15.419) (Hightlighted by X-Mol)

16. Wei, W.-X.; Li, Y.; Wen, Y.-T.; Li, M.; Li, X.-S.; Wang, C.-T.; Liu, H.-C.; Xia, Y.; Zhang, B.-S.; Jiao, R.-Q.; Liang, Y.-M., Experimental and Computational Studies of Palladium-Catalyzed Spirocyclization via a Narasaka–Heck/C(sp3 or sp2)–H Activation Cascade Reaction. J. Am. Chem. Soc. 2021, 143 (20), 7868-7875. (SCI 一区, IF 15.419) (Hightlighted by X-Mol)

专利

1. 梁永民; 张博生, 一种4-氨基吲哚的合成方法, China Patent No. 201910307811.9.